Scientific Benefits of Phosphatidylserine - Body of Harmony

Scientific Benefits of Phosphatidylserine

by: Payam Hakimi
March 2025
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Phosphatidylserine (PS) is a naturally occurring phospholipid found in high concentrations in the brain. It plays a crucial role in cellular function, especially in nerve cells, and has been extensively studied for its cognitive, stress-reducing, and neuroprotective benefits.

1. Cognitive Function & Memory

How It Helps: PS supports neurotransmitter activity and enhances brain cell communication, which is essential for memory formation and cognitive processing.
Scientific Evidence: A study published in Aging (1993) found that PS supplementation improved memory, learning, and recall in older adults with mild cognitive decline.
Study: Crook et al., Aging (Milano), 1993.

2. Reduces Stress & Cortisol Levels

How It Helps: PS helps regulate cortisol, the stress hormone, reducing the physiological impact of stress.
Scientific Evidence: A study in Sports Medicine (2008) found that PS supplementation reduced cortisol levels in athletes after intense exercise, improving recovery and mood.
Study: Kingsley et al., Sports Medicine, 2006.

3. Supports ADHD Management

How It Helps: PS enhances dopamine levels and improves attention, focus, and hyperactivity in children with ADHD.
Scientific Evidence: A double-blind study found that children with ADHD who took PS experienced improved attention and impulse control.
Study: Hirayama et al., Journal of Human Nutrition and Dietetics, 2014.

4. Improves Exercise Performance & Recovery

How It Helps: PS reduces muscle soreness, enhances endurance, and improves athletic performance by decreasing stress-induced inflammation.
Scientific Evidence: Research shows that PS supplementation can decrease perceived muscle soreness and improve reaction times in athletes.
Study: Starks et al., Journal of the International Society of Sports Nutrition, 2008.

5. Neuroprotective Effects & Potential for Alzheimer’s Disease

How It Helps: PS supports neuronal repair and protects against cognitive decline by maintaining cell membrane integrity.
Scientific Evidence: Studies suggest that PS supplementation may slow cognitive decline in individuals with Alzheimer's disease and other forms of dementia.
Study: Glade et al., Nutrition, 2010.

6. Enhances Mood & Reduces Symptoms of Depression

How It Helps: PS interacts with serotonin and dopamine, neurotransmitters linked to mood regulation.
Scientific Evidence: A study found that PS combined with omega-3 fatty acids reduced symptoms of depression in elderly individuals.
Study: Kato-Kataoka et al., Lipids in Health and Disease, 2010.

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