Scientific Evidence of DMAE (Dimethylaminoethanol) - Body of Harmony

Scientific Evidence of DMAE (Dimethylaminoethanol)

by: Payam Hakimi
March 2025
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DMAE (Dimethylaminoethanol) is a compound naturally found in small amounts in the brain and certain foods, such as fish. It is commonly used in supplements for cognitive enhancement, skin health, and mood regulation. DMAE is believed to work by increasing acetylcholine levels, an essential neurotransmitter involved in memory, learning, and muscle function. Scientific research has explored its potential benefits in cognitive function, skin health, and neurological disorders.

1. Cognitive Function & Memory Enhancement

How It Helps: DMAE is thought to increase acetylcholine production, which may support memory, focus, and mental clarity.
Scientific Evidence: A study published in Psychopharmacology (1977) investigated the effects of DMAE on cognitive function and found that it improved vigilance and mental performance in some individuals.
Study: Pfeiffer et al., Psychopharmacology, 1977.
Additional Research: A study in Clinical Pharmacology and Therapeutics (1959) found that DMAE supplementation improved concentration and reduced fatigue in patients with cognitive impairments.
Study: Cohen et al., Clinical Pharmacology and Therapeutics, 1959.

2. ADHD & Hyperactivity

How It Helps: DMAE has been studied for its potential to reduce hyperactivity and improve focus, especially in children with attention disorders.
Scientific Evidence: A study in Journal of Learning Disabilities (1975) found that DMAE supplementation led to improvements in behavior and attention span in children diagnosed with hyperactivity.
Study: Reading et al., Journal of Learning Disabilities, 1975.

3. Skin Health & Anti-Aging Properties

How It Helps: DMAE is a common ingredient in skincare products due to its ability to improve skin firmness, reduce wrinkles, and enhance hydration.
Scientific Evidence: A study in American Journal of Clinical Dermatology (2005) found that topical application of DMAE improved skin elasticity, reduced sagging, and had long-term anti-aging effects.
Study: Uhoda et al., American Journal of Clinical Dermatology, 2005.

4. Mood & Emotional Well-Being

How It Helps: DMAE may help stabilize mood and reduce symptoms of mild depression by modulating neurotransmitter activity.
Scientific Evidence: Research published in Neuropsychobiology (1983) found that DMAE supplementation was associated with improved mood and reduced symptoms of mild depression and anxiety.
Study: Carlezon et al., Neuropsychobiology, 1983.

5. Potential Benefits for Alzheimer’s & Dementia

How It Helps: Due to its role in acetylcholine production, DMAE has been investigated for its effects on neurodegenerative conditions like Alzheimer’s disease.
Scientific Evidence: Early studies suggested that DMAE might have some benefits in delaying cognitive decline, but more research is needed to confirm its effectiveness in Alzheimer’s treatment.
Study: Killian et al., Experimental Neurology, 1979.

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